Back in the days when my kids were very young, one of them would occasionally come down with a cold or the flu. With three kids, it seemed like at least one of them would be sick fairly often. And when two or more kids were sick, there wasn’t a lot of sleeping for me.

I personally do not get sick very often—although after a few nights of being up with sick kids and missing out on valuable sleep–BOOM! I’d be sick too.

Now that my kiddos are all grown up, I travel frequently–and traveling to faraway places means a long flight, usually cramped up in a seat, trying to sleep while flying through several time zones. The sleep deprivation that results from a day’s worth (or more) of traveling and time zone changes almost always causes me to end up getting sick.

I’m convinced there has to be a big connection between sleep and immune function.

Turns out there is. People who generally sleep six hours or less have altered immune responses, in several different parts of the immune system. Sleep deprivation especially impacts the body’s white blood cells, which are part of the innate immune system, the body’s first line of defense against invading pathogens.

In one study of identical twins, conducted at University of Washington’s Sleep Center, it was found that the twin who got the least amount of sleep was more likely to get sick. Lead scientist in the study, Dr. Nathaniel Watson said, “What we show is that the immune system functions best when the body gets enough sleep. Seven or more hours of sleep is recommended for optimal health.”

Sleep deprivation can also actually increase inflammatory markers and over-activate immune cells. The study showed for the first time that chronic sleep deprivation (less than six hours a night) shuts down the immune response effectiveness of circulating white blood cells.

Sleep is so essential to immune system function that sleep deprived people don’t even develop a very strong antibody response to a vaccine.

How does sleep affect your immune system?

The Innate Immune System, the Body’s First Line of Defense

Our immune system–while complex--has two basic functions. One is the innate immune system, which is our body’s first line of defense against any invading pathogens. Its purpose is to disable or kill any invader before it has a chance to enter our cells and reproduce.

Research shows that sleep deprivation has a strong negative effect on the innate immune system, which acts immediately to prevent the spread and movement of foreign pathogens.

One study of looked at exposure to the common cold virus among two groups–one that had more than 7 hours of sleep and the other with less than 6 hours of sleep. The group that got less than 6 hours of sleep were four times more likely to be infected than the group that got more than 7 hours of nightly rest.

The white blood cells and immune proteins that work as barriers to kill off infecting pathogens in the innate immune system are weakened by sleep deprivation.

T Cell Function

Numerous studies have looked at the benefits of a good night’s sleep, and researchers from Germany have found that sound sleep improves a vital part of the immune system in cells known as T cells. T cells are an essential part of the body’s immune system, critical to the immune response.

T cells are a type of immune cell that fight against pathogens that make their way into a cell, such as virus-infected cells including Covid19, all types of influenza, HIV, herpes, and cancer cells.

When T cells recognize a pathogen or an infected target cell, such as a cell infected with a virus, they activate proteins that attach to their target and, in the case of a virally infected cell, kill it.

The researchers compared T cells from healthy volunteers who either slept or stayed awake all night. The T cells in the well-rested participants showed higher levels of activation than in the T cells of those who had not slept.

For people who get poor sleep, stress hormones such as cortisol and adrenaline also tend to rise, and these stress hormones also tend to dampen the ability of T cells to fight off pathogens effectively, as well as raising inflammation levels.

These findings show that sleep has the potential to enhance the efficiency of T cell responses, which is especially important considering that sleep disorders are also tied to mental health conditions such as depression, chronic stress, and aging.

Cytokines and Inflammation

During sleep, your immune system also releases proteins called cytokines, some of which help promote sleep. Certain cytokines also play a role when you have an infection or inflammation, or when you’re under stress.

Cytokines are actually a set of proteins that serve as chemical messengers. These proteins, tell immune cells what to do and also tell the body to produce more of them to help deliver a knockout blow, if necessary, to the infection.

Sleep deprivation has been shown to decrease the production of these protective cytokines. In addition, infection-fighting antibodies and cells are reduced during periods when you don’t get enough sleep.

Sleep also helps reduce stress hormones while raising helpful sleep hormones such as melatonin. Melatonin is a hormone made naturally by your body and produced in the pineal gland in the brain.

Melatonin is considered the sleep hormone as its rising levels at night help you fall asleep and sleep more soundly. Melatonin is also a powerful antioxidant, which may provide a variety of other health benefits, including strengthening the immune system.

Cytokines can be pro-inflammatory, increasing an inflammatory response from the immune system. Other inflammatory cytokines also increase with shorter sleep periods, and one in particular, IL-17 can remain elevated up to two days after recovery sleep.

In severe cases of the flu or Covid19, cytokine production can grow out of control. Immune cells release cytokines that tell the body to produce more immune cells, and in turn these new cells release even more pro-inflammatory cytokines.

These excessive amounts of cytokines can lead to something called a cytokine storm, which creates an overwhelming inflammatory immune response that can damage lungs and kidneys and bring about death. Cytokine storms are one of the reason that many people die from Covid19.

Sleep can help to modulate–or slow down–the effects of an over-reaction of cytokines while protecting and balancing the immune system. Sleep also helps to lower inflammation, including CRP levels (an inflammatory marker), while strengthening the overall immune response.

Adults should have a minimum of seven hours of sleep on a regular basis for improved health, lower stress levels and lower inflammation. A good night’s sleep also goes a long ways towards protecting your health and effectively fighting off dangerous pathogens such as Covid19, flu and even colds.

Unfortunately, more one third of American adults are getting less than seven hours of sleep, according to a study in 2016 from the Centers for Disease Control and Prevention.

Less than five hours of sleep a night on a regular basis is actually associated with higher ‘all-cause’ mortality, increased risk of depression, stress, infections, weight gain, and blood sugar issues.

Key to remember:

• Try to go to sleep at around the same time every night and get up at the same time.
• Avoid too much alcohol or heavy meals right before bed.
• Avoid hard workouts right before bedtime.
• Get plenty of exercise during the day.
• Get out in the sunshine daily.
• Avoid stimulants such as caffeine, within 6 hours of bedtime.
• Try to ease stress and if necessary, try a pre-bedtime meditation.
• Avoid looking at your phone or computer right before bedtime.

If necessary, take a healthy natural supplement containing natural melatonin to help you get sleepy and sleep more soundly, as well as giving a try to this delicious HOT golden latte. Drink right before bed, if you struggle with “winding down” and relaxing at the end of the day, or falling asleep at night.

Not only will it help you relax and fall asleep, but it’ll help you STAY asleep, providing for a more restful night, and let you wake up feeling refreshed, rejuvenated, and full of energy

> Drink this HOT Golden Latte 1hr before bed to sleep better, fight inflammation, & wake up feeling refreshed

Take 1 sip an hour before bed to boost your Growth Hormone and flatten your belly while you sleep:

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>> Take 1 sip an hour before bed to boost fat-burning hormones while you sleep (boosts GH while also helping you to sleep deeper)

References
https://todayspractitioner.com/sleep/sleep-cytokines-and-inflammation/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102583/
https://www.healthline.com/health-news/how-sleep-bolsters-your-immune-system#The-importance-of-T-cells
https://www.medicalnewstoday.com/articles/324432#Sleep-could-enhance-T-cell-responses
https://www.sciencedaily.com/releases/2019/02/190212094839.htm
https://rupress.org/jem/article/216/3/517/120367/G-s-coupled-receptor-signaling-and-sleep-regulate
https://www.ucihealth.org/blog/2020/04/sleep-immunity-covid

The post Sleep Deprivation: How it Affects Your Immune System to Fight Off Viruses appeared first on thenutritionwatchdog.com.

By: Cat Ebeling, RN, MSN-PHN, co-author of the best-sellers:  The Fat Burning Kitchen, The Top 101 Foods that Fight Aging & The Diabetes Fix

I have been taking Vitamin C to prevent colds and the flu since the 70’s, when Linus Pauling declared vitamin C’s ability to defeat the common cold. I have always thought it helped prevent or shorten any illness. Since then, it’s been a hotly debated subject as to how effective it actually is for preventing colds, and influenza. Personally, I am a believer.

Vitamin C is a very potent antioxidant that protects against free radicals that can lower your immunity, and increase the risk of chronic disease, as well as speed up the aging process.

Vitamin C does help the immune system protect against viral infections and other types of infections more efficiently. It does this by strengthening the function of our innate immune system, which is our first line of defense against bacteria and viruses—especially those we have never encountered before.

In addition, vitamin C also activates the adaptive immune system responses to increase levels of antibodies which attack specific types of germs, bacteria and viruses that the body has previously fought off.

One of the hallmark signs of vitamin C deficiency is a weakened immune system.  A study out of Switzerland found that getting adequate levels of vitamin C can help reduce the symptoms and duration of respiratory infections, such as the common cold, bronchitis, or sinusitis. And, when combined with zinc, more importantly, it can also prevent or improve outcomes of pneumonia, malaria and diarrhea infections as well.

Some of the most convincing evidence of vitamin C’s ability to fight respiratory infections comes from a large study of 29 randomized trials that included more than 11,000 participants. Researchers found that active athletes who exercised in cold weather cut their risk of respiratory infections in half by taking only 200mg of vitamin C a day. Taking just 200mg of vitamin C per day also reduced the duration of the cold and flu symptoms significantly, helping people return to work and their lives more quickly.

Vitamin C is also effective at both preventing cancer cells and stopping their spread. A study from Finland shows vitamin C’s ability to help prevent heart disease—people who took 700mg of vitamin C a day had a 25% lower chance of developing heart disease, as well as lowering both triglycerides and levels of (bad) LDL cholesterol.

Unfortunately, humans are one of the only species who cannot create vitamin C in their bodies. So we must get it from our diets and supplementation. Vitamin C is also water soluble, so it easily washes out of the body. If you want the benefits of vitamin C, you’ll need to consume it daily, and not just at the start of getting sick.
While high doses of vitamin C may be effective at helping with some health issues, most of the vitamin C over 400 mg may get washed out in the urine. High doses of vitamin C work best in divided doses throughout the day, otherwise, it may cause digestive upset and diarrhea.

A recent study published in Seminars in Preventive and Alternative Medicine looked at over 100 studies and found a growing list of benefits of vitamin C. Some of those health benefits include:

• Protecting against heart disease, high blood pressure and strokes
• Lowering bad cholesterol levels including LDL and triglycerides
• Helping prevent cataracts and macular degeneration
• Reducing aging by building up collagen that prevents wrinkles
• Protecting the kidneys, eyes and blood vessels of those with diabetes
• Enhancing the absorption of iron, preventing anemia
• Reducing histamine reactions, lessening the symptoms of allergies and inflammation
• Preventing seasickness
• Strengthening and helping repair tendons, ligaments, and cartilage in the body.

Since we don’t make vitamin C, it’s easy to become deficient in it. Some of the signs of low vitamin C include:

• Bruising
• Swollen or bleeding gums
• Slow wound healing
• Dry hair
• Rough scaly skin
• Nosebleeds
• Weak immune system, frequent colds and flu
• Digestive disorders like leaky gut and food allergies
• High blood pressure and heart disease

Because the vitamin C in foods is accompanied by a host of other healthy antioxidants and super nutrients, it’s best to eat foods with high vitamin C content. Some of the highest levels of vitamin C in foods include all forms of citrus fruits, kiwi, peppers—especially red peppers, papaya, strawberries, broccoli, tomatoes, kale, guava, and mango. But it’s easy to get plenty of healthful vitamin C just by choosing a wide variety of organic, brightly colored vegetables. Keep in mind that overcooking destroys the vitamin C, so cook lightly or eat raw.

However, you should probably still consider supplementing to achieve the optimal protective levels of vitamin C in your body. While high doses are generally safe, it is still important not to exceed the and upper limit of about 2,000 milligrams a day to avoid adverse digestive symptoms such as stomach upset and diarrhea.

Liposomal (or pro-liposomal) vitamin C is a brand new highly absorbable option for high-dose vitamin C. When you take the common form of ascorbic acid (vitamin C) only about 14-30% of it is actually absorbed in the body. And the absorption rate goes down, the higher the dosage. Dosage of standard forms of vitamin C are only about 200-1,000 mg/day but with liposomal vitamin C you can safely take 1000-2000mg a day and know it will all be absorbed.

This is where liposomal vitamin C has an advantage.

Liposomes are particular microscopic spheres that carry vitamin C at their core. Their absorption does not depend on vitamin C transporters, but rather on the direct fusion of the liposome with the small intestinal cells resulting in direct intracellular (inside the cells) release of the vitamin C and eventually into the blood circulation. Liposomal vitamin C has a substantially improved rate of absorption than conventional vitamin C supplements which further magnifies all the health benefits of vitamin C.

Experts agree that Vitamin C, in combination with a healthy lifestyle, can boost your immune system and help prevent colds and flu, or shorten the duration.

We put one of the worst modern health crisis in our rear view mirror, but is it really over?

2026 – ER doc has urgent immunity warning for what’s coming

According to one ER doctor, there are 3 terrifying warning signs right now…

The media is hiding them (the politicians needed votes this fall).

Click here to see what’s coming next, and how to protect yourself

Immunity has been the perfect “back door” for taking away our freedoms..

And, what comes next could make the last few years look like a cakewalk.

Here’s this MD’s suggestions for supporting your immune system right now.

References
https://coremedscience.com/blogs/wellness/how-to-pick-the-best-liposomal-vitamin-c
https://lpi.oregonstate.edu/mic/vitamins/vitamin-C#common-cold-treatment
https://www.healthline.com/nutrition/vitamin-c-coronavirus#recommendation
https://draxe.com/nutrition/vitamin-c-foods/
https://www.medicalnewstoday.com/articles/219352#what_is_vitamin_C_and_why_do_we_need_it

The post Vitamin C and Your Immune System appeared first on thenutritionwatchdog.com.