Back in the days when my kids were very young, one of them would occasionally come down with a cold or the flu. With three kids, it seemed like at least one of them would be sick fairly often. And when two or more kids were sick, there wasn’t a lot of sleeping for me.

I personally do not get sick very often—although after a few nights of being up with sick kids and missing out on valuable sleep–BOOM! I’d be sick too.

Now that my kiddos are all grown up, I travel frequently–and traveling to faraway places means a long flight, usually cramped up in a seat, trying to sleep while flying through several time zones. The sleep deprivation that results from a day’s worth (or more) of traveling and time zone changes almost always causes me to end up getting sick.

I’m convinced there has to be a big connection between sleep and immune function.

Turns out there is. People who generally sleep six hours or less have altered immune responses, in several different parts of the immune system. Sleep deprivation especially impacts the body’s white blood cells, which are part of the innate immune system, the body’s first line of defense against invading pathogens.

In one study of identical twins, conducted at University of Washington’s Sleep Center, it was found that the twin who got the least amount of sleep was more likely to get sick. Lead scientist in the study, Dr. Nathaniel Watson said, “What we show is that the immune system functions best when the body gets enough sleep. Seven or more hours of sleep is recommended for optimal health.”

Sleep deprivation can also actually increase inflammatory markers and over-activate immune cells. The study showed for the first time that chronic sleep deprivation (less than six hours a night) shuts down the immune response effectiveness of circulating white blood cells.

Sleep is so essential to immune system function that sleep deprived people don’t even develop a very strong antibody response to a vaccine.

How does sleep affect your immune system?

The Innate Immune System, the Body’s First Line of Defense

Our immune system–while complex--has two basic functions. One is the innate immune system, which is our body’s first line of defense against any invading pathogens. Its purpose is to disable or kill any invader before it has a chance to enter our cells and reproduce.

Research shows that sleep deprivation has a strong negative effect on the innate immune system, which acts immediately to prevent the spread and movement of foreign pathogens.

One study of looked at exposure to the common cold virus among two groups–one that had more than 7 hours of sleep and the other with less than 6 hours of sleep. The group that got less than 6 hours of sleep were four times more likely to be infected than the group that got more than 7 hours of nightly rest.

The white blood cells and immune proteins that work as barriers to kill off infecting pathogens in the innate immune system are weakened by sleep deprivation.

T Cell Function

Numerous studies have looked at the benefits of a good night’s sleep, and researchers from Germany have found that sound sleep improves a vital part of the immune system in cells known as T cells. T cells are an essential part of the body’s immune system, critical to the immune response.

T cells are a type of immune cell that fight against pathogens that make their way into a cell, such as virus-infected cells including Covid19, all types of influenza, HIV, herpes, and cancer cells.

When T cells recognize a pathogen or an infected target cell, such as a cell infected with a virus, they activate proteins that attach to their target and, in the case of a virally infected cell, kill it.

The researchers compared T cells from healthy volunteers who either slept or stayed awake all night. The T cells in the well-rested participants showed higher levels of activation than in the T cells of those who had not slept.

For people who get poor sleep, stress hormones such as cortisol and adrenaline also tend to rise, and these stress hormones also tend to dampen the ability of T cells to fight off pathogens effectively, as well as raising inflammation levels.

These findings show that sleep has the potential to enhance the efficiency of T cell responses, which is especially important considering that sleep disorders are also tied to mental health conditions such as depression, chronic stress, and aging.

Cytokines and Inflammation

During sleep, your immune system also releases proteins called cytokines, some of which help promote sleep. Certain cytokines also play a role when you have an infection or inflammation, or when you’re under stress.

Cytokines are actually a set of proteins that serve as chemical messengers. These proteins, tell immune cells what to do and also tell the body to produce more of them to help deliver a knockout blow, if necessary, to the infection.

Sleep deprivation has been shown to decrease the production of these protective cytokines. In addition, infection-fighting antibodies and cells are reduced during periods when you don’t get enough sleep.

Sleep also helps reduce stress hormones while raising helpful sleep hormones such as melatonin. Melatonin is a hormone made naturally by your body and produced in the pineal gland in the brain.

Melatonin is considered the sleep hormone as its rising levels at night help you fall asleep and sleep more soundly. Melatonin is also a powerful antioxidant, which may provide a variety of other health benefits, including strengthening the immune system.

Cytokines can be pro-inflammatory, increasing an inflammatory response from the immune system. Other inflammatory cytokines also increase with shorter sleep periods, and one in particular, IL-17 can remain elevated up to two days after recovery sleep.

In severe cases of the flu or Covid19, cytokine production can grow out of control. Immune cells release cytokines that tell the body to produce more immune cells, and in turn these new cells release even more pro-inflammatory cytokines.

These excessive amounts of cytokines can lead to something called a cytokine storm, which creates an overwhelming inflammatory immune response that can damage lungs and kidneys and bring about death. Cytokine storms are one of the reason that many people die from Covid19.

Sleep can help to modulate–or slow down–the effects of an over-reaction of cytokines while protecting and balancing the immune system. Sleep also helps to lower inflammation, including CRP levels (an inflammatory marker), while strengthening the overall immune response.

Adults should have a minimum of seven hours of sleep on a regular basis for improved health, lower stress levels and lower inflammation. A good night’s sleep also goes a long ways towards protecting your health and effectively fighting off dangerous pathogens such as Covid19, flu and even colds.

Unfortunately, more one third of American adults are getting less than seven hours of sleep, according to a study in 2016 from the Centers for Disease Control and Prevention.

Less than five hours of sleep a night on a regular basis is actually associated with higher ‘all-cause’ mortality, increased risk of depression, stress, infections, weight gain, and blood sugar issues.

Key to remember:

• Try to go to sleep at around the same time every night and get up at the same time.
• Avoid too much alcohol or heavy meals right before bed.
• Avoid hard workouts right before bedtime.
• Get plenty of exercise during the day.
• Get out in the sunshine daily.
• Avoid stimulants such as caffeine, within 6 hours of bedtime.
• Try to ease stress and if necessary, try a pre-bedtime meditation.
• Avoid looking at your phone or computer right before bedtime.

If necessary, take a healthy natural supplement containing natural melatonin to help you get sleepy and sleep more soundly, as well as giving a try to this delicious HOT golden latte. Drink right before bed, if you struggle with “winding down” and relaxing at the end of the day, or falling asleep at night.

Not only will it help you relax and fall asleep, but it’ll help you STAY asleep, providing for a more restful night, and let you wake up feeling refreshed, rejuvenated, and full of energy

> Drink this HOT Golden Latte 1hr before bed to sleep better, fight inflammation, & wake up feeling refreshed

Take 1 sip an hour before bed to boost your Growth Hormone and flatten your belly while you sleep:

Recent studies are now showing how a simple tweak to your bedtime ritual can have dramatic effects in shrinking fat tissue while reversing the signs of premature biological aging every time you fall asleep.

This pre-bedtime daily ritual also helps you sleep deeper while increasing specific hormones that FORCE your body to release stored abdominal fat while you sleep… AND it works equally well for BOTH men and women, as you’ll see below…

>> Take 1 sip an hour before bed to boost fat-burning hormones while you sleep (boosts GH while also helping you to sleep deeper)

References
https://todayspractitioner.com/sleep/sleep-cytokines-and-inflammation/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102583/
https://www.healthline.com/health-news/how-sleep-bolsters-your-immune-system#The-importance-of-T-cells
https://www.medicalnewstoday.com/articles/324432#Sleep-could-enhance-T-cell-responses
https://www.sciencedaily.com/releases/2019/02/190212094839.htm
https://rupress.org/jem/article/216/3/517/120367/G-s-coupled-receptor-signaling-and-sleep-regulate
https://www.ucihealth.org/blog/2020/04/sleep-immunity-covid

The post Sleep Deprivation: How it Affects Your Immune System to Fight Off Viruses appeared first on thenutritionwatchdog.com.

By: Cat Ebeling, RN, MSN-PHN, co-author of the best-sellers:  The Fat Burning Kitchen, The Top 101 Foods that Fight Aging & The Diabetes Fix

Vitamin D from the sun has existed for a long time as an immune booster. In the 1800’s when many people had tuberculosis, sunshine was known to have curative powers, and sick patients flocked to sanitariums in sunny places to soak up the healing sunshine. Cod liver oil, also a rich source of vitamin D, has also been around for decades as a preventative for infections, colds and flu.

Studies show that vitamin D regulates many functions in the body, including hormone balance, metabolism, blood pressure, bone density, fighting cancer, and immune function (ever notice that people tend to get colds and flu in the winter when the sun is low?).

Vitamin D is critical for our health. We know that vitamin D is essential for healing and protecting against many contagious diseases and chronic diseases. Low levels of vitamin D are associated with upper and lower respiratory infections, heart disease, asthma, cancers, diabetes, multiple sclerosis, HIV, hypertension, inflammatory bowel disease, Alzheimer’s disease and other autoimmune diseases. Vitamin D deficiency is a worldwide public health problem in both developed and developing countries.

Did you know that our bodies contain cell receptors for vitamin D in virtually every system of the body? That tells us that vitamin D is necessary for virtually all body functions. Vitamin D actually influences the expression of over 200 health-supporting genes in our bodies.

There’s a lot of buzz about vitamin D boosting immune function to fight off colds, seasonal influenza, and other viruses. Research suggests that vitamin-D deficiency may one of the primary reasons people get more colds and flu in the winter when sunshine is less available.

As many as 70 percent of Americans are considered deficient in vitamin D. The elderly, females more than males, those who live the far north or south of the equator, people with darker skin pigmentation, those who work and stay inside during the day, and people with poor dietary habits generally have the lowest levels of vitamin D.

How does vitamin D boost immune function?

The immune system is an incredibly complex protective mechanism, but to simplify, we can divide the immune system into two main categories: innate immunity, and adaptive immunity.

Innate immunity is our nonspecific defense mechanism that activates in the presence of an invading pathogen. So, even if you have never been exposed to a virus or pathogen, your body has a built-in ability to protect itself from an invader. This part of your immune system is your first line of defense against any type of new type of germs—whether it is bacteria, viruses, and fungi. And it’s super important to be sure this line of defense is strong.

The other type of immune response is your adaptive immune response. This immune response is active against pathogens that you have previously encountered. The body recognizes, adapts and attacks specific invaders much more efficiently.

In the case of brand new types of influenza strains, the body has not had a chance to develop specific antibodies against it yet. So, this is where we call in the powers of our innate immune system to protect us. Vitamin D works to strengthen this innate immune system response.

Many different studies have associated vitamin D with its power to fight infection. One report looked at almost 19,000 people and found that the individuals with the lower levels of vitamin D were more likely to report upper respiratory tract infections, than those with sufficient levels of vitamin D.

This study looked at 800 people in Finland, and found that those with the lowest levels of vitamin D lost more days at work due to respiratory infections. Other studies have focused on how vitamin D helps to prevent influenza, colds and even HIV. And this well-designed study using therapeutic doses of vitamin D showed that vitamin D administration resulted in a statistically significant (42%) decrease in the incidence of influenza infection.

Vitamin D works by boosting the strength of the immune system while lowering inflammatory reactions. This makes vitamin D a powerful immune modulator. It helps boost immune power, but prevents the immune system from overreacting, as in the case of autoimmune disease.

How does it work? Vitamin D strengthens particular cells within the immune system, such as the T cells. It also helps to decrease levels of inflammatory cytokines, a part of the immune system that can overreact with dangerous outcomes.

There are three ways to get vitamin D levels up in your system. One—you can take a vitamin D3 supplement. D3 or cholecalciferol is most easily utilized in the body, over vitamin D2. Secondly, you can get some vitamin D from foods and third, you can get vitamin D from the sun—IF you are in an area where the sun is strong enough. Depending on the latitude where you live and the time of year, you may or may not be able to get vitamin D from the sun. In my opinion, however getting vitamin D from sunshine is the best way if you can.

The sun’s rays are too weak in the winter generally (depending on the latitude that you live). Even if you can get outside in the winter, if you live north of say, Los Angeles to the west and Atlanta Georgia to the east, you won’t be able to get enough sun from November through February.

The only way for our bodies to make vitamin D from the sun is to allow the UVB rays of the sun to reach our skin. That means we need to expose enough skin for 20-40 minutes without sunscreen at the strongest times of the day, between the hours of 10am and 2pm.

UVB rays are the rays that cause sunburn, just don’t overdo it! Full-body exposure of pale skin to summer sunshine for 30 minutes without clothing or sunscreen can result in the synthesis of between 10,000 and 20,000 IU of vitamin D.

However—if you don’t supplement with vitamin D3 in the winter you’re can pretty much count on being deficient in vitamin D in the winter.

Supplementing with vitamin D has a wide range of ‘suggested’ dosages, and you can overdo it with this fat soluble vitamin and create adverse health effects. While some doctors advise people to take 5000 to 10,000 Iu per day of vitamin D, this can be too much and a safer range would be around 5,000IU vitamin D3 per day.

According to Dr. Chris Kresser, the fat-soluble vitamins A, D, and K work synergistically, so adding adequate vitamin A and K2 may protect against toxic effects of excess vitamin D. Sufficient levels of potassium and magnesium have also been suggested to protect against vitamin D toxicity.

Lastly, be sure to get plenty of healthy food with natural sources of vitamin D, such as egg yolks, wild caught salmon and mackerel, organ meats, and some mushrooms. And avoid those processed foods with added vitamin D—those do nothing for your health.

Some of the best absorbed vitamin D comes from taking some cod liver oil daily. Make sure to take only small doses of cod liver oil (enough for 50% to 100% DV of vitamin D), as large doses can give you an overdose of Vitamin A.

One more thing to point out as we near the end of winter, sunlight has far more beneficial benefits for our health than just increasing our vitamin D.

A recent 20-year study following 29,518 subjects found that those individuals avoiding sun exposure were twice as likely to die from all causes. Sunlight helps us make more endorphins, the natural chemical in our bodies that makes us feel relaxed and happy.

Sunlight promotes production of a peptide that helps to dilate the blood vessels, lowering blood pressure, and it helps create another substance called ‘Substance P’, that promotes better blood flow and regulates the immune system in response to acute stressors. And one more benefit of sunshine, it helps to reduce appetite, increase the libido and gives you a nice looking golden glow, while regulating your sleeping/waking cycle better.

If you want to stay healthy and strong, it’s not only wise, but essential to spend time outdoors in the sunshine. Soak it up!

We put one of the worst modern health crisis in our rear view mirror, but is it really over?

2026 – ER doc has urgent immunity warning for what’s coming

According to one ER doctor, there are 3 terrifying warning signs right now…

The media is hiding them (the politicians needed votes this fall).

Click here to see what’s coming next, and how to protect yourself

Immunity has been the perfect “back door” for taking away our freedoms..

And, what comes next could make the last few years look like a cakewalk.

Here’s this MD’s suggestions for supporting your immune system right now.

References
https://www.nytimes.com/2020/03/10/well/live/can-i-boost-my-immune-system.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166406/
https://chriskresser.com/vitamin-d-more-is-not-better/
https://www.sciencedaily.com/releases/2019/04/190417111440.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821804/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738984/#B7-nutrients-05-02502
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738984/

The post Vitamin-D and Immune Function appeared first on thenutritionwatchdog.com.

With the rapid spread of Covid-19 around the world, along with the dramatic and scary news stories, it seems everyone is scrambling to grab supplements to boost their immune systems. While nothing takes the place of a healthy diet that lowers inflammation in your body, a good night’s sleep, stress reduction, exercise, and vitamin D production in your skin from sun exposure—some supplements can definitely be helpful as well.

Once the SARS-CoV-2 or Coronavirus gets inside the human respiratory tract, it infects and multiplies in the cells lining the airways and lungs. This kicks the body’s immune system into action. In most people, the immune system does its work, then recedes and the patient recovers.

Normally, an immune response which causes inflammation is a normal and good thing in the fight against a pathogen or an injury. However, with this coronavirus, the Acute Respiratory Distress Syndrome that occurs in some people, happens as a result of a dysfunctional immune response to the presence of the virus. The uncontrolled immune response triggers an overproduction of immune cells and their signaling molecules which leads to a ‘cytokine storm’. This cytokine storm is generally what causes the severe and potentially fatal symptoms of severe pneumonia and breathing difficulties with a Covid19 infection.

So it’s more about having a healthy immune system overall and reducing inflammation in the body, because if the body is already overridden with inflammation, leaky gut, Diabetes, obesity, and other health problems, it’s possible this can contribute to the cytokine storm that’s being seen in some patients.

There are several supplements that actually help to strengthen the immune system and reduce inflammation, without overstimulating the immune system. One of the top nutrients for this is Quercetin.

What is Quercetin?  It is a potent anti-inflammatory and antiviral substance found in certain foods, including red onions and apples. Many people take Quercetin in the fall and spring to help their allergies to tree and weed pollen.  Quercetin has been shown in many studies to have fairly broad anti-viral properties against most viruses.

Quercetin is considered a bioflavonoid. Quercetin is found in the highest concentrations in red onions, berries, red wine, green tea, buckwheat, and apples.

Quercetin is now also undergoing trials in China for its effectiveness against Covid19 (but I am in no way saying Quercetin cures or blocks your ability to get it). In a recent analysis published by the University of Tennessee and Oak Ridge National Labs, they used high-powered computer modeling to look at which compounds or supplements might best prevent the coronavirus from binding to our cells.

This is key, because this is how this virus gets into to our bodies and starts reproducing. It enters our bodies through nasal passages, mouth, eyes, or respiratory passages. Once it binds to a cell, it finds its way into the cell, starts reproducing like crazy, and takes over the respiratory system, especially the lungs.

The coronavirus uses the ACE2 or Angiotensin Converting Enzyme receptor in our bodies to enter the cells. This is important too, because ACE2 receptors have to do with regulating our blood pressure—I’ll talk more about that below.

The analysis from Tennessee looked at several different compounds and nutrients to see which ones worked best at interfering with the virus’s ability to attach to a cell and get inside to do its damage. One of the top 5 virus-fighting natural compounds is Quercetin.

Quercetin is a natural supplement that has other big benefits including lessening reactions to allergies, as well as fighting aging and free radicals. Well worth it to start taking since it has multiple benefits for our health. According to most research, the usual dose is 500mg to 1,000 mg a day. Quercetin is often compounded with a digestive enzyme like bromelain, plus Vitamin C, to improve absorption. All good things.

Quercetin is also inexpensive, especially compared to some of the pharmaceutical grade antiviral drugs that are being used now. This broad-spectrum antiviral supplement has already proven successful for treating the Ebola and Zika viruses, according to Dr. Michel Chrétien, a researcher at the Clinical Research Institute of Montreal.

Does it work for sure? It’s too early for standard clinical trials to show positive proof, but the circumstantial evidence is strong in favor of its anti-inflammatory and antiviral capabilities. The best thing about quercetin is, even without clinical trials, we know that quercetin will not harm you, or cause your immune system to overreact. Including quercetin in your immune-boosting weapons seems like a wise idea, along with these other practices as well:

Get good sleep

Poor sleep increases the risk of infectious illness. One study found that getting less than 5 hours of sleep over the course of a week, can increase the chances of catching a cold by 350%. Also, important to note is that lack of sleep can increase inflammatory levels in the body, creating higher risk for a cytokine storm. If you are having trouble sleeping, a small dose of melatonin at night may help you sleep better and keep your immune system strong.

Manage your stress

It’s no secret that stress definitely disrupts our immune function and increases our levels of inflammation, making us far more susceptible to getting seriously ill. Stop reading the news, follow precautions and find something relaxing to do—meditation, breathing exercises and exercising outdoors all go a long way to manage stress, reduce anxiety and strengthen your immune system.

Take Zinc

Zinc has been proven to reduce the activity of coronavirus and may prevent its entry into our cells while reducing its power. Zinc has proven powerful in fighting off regular influenza and the common cold as well. The suggested dosage for zinc is about 15mg – 30mg daily.

Vitamin C

Vitamin C has shown great promise in inhibiting inflammatory reactions and is thought to be very effective against viruses as well.  Several clinical trials have found that vitamin C shortens the frequency, duration and severity of the virus that causes the common cold (a type of corona virus) and the incidence of pneumonia. Vitamin C can be taken in reasonably high doses as any excess is washed out of the body.

Eat Other Immune-Boosting Nutrients:

Other foods to consider including in your diet are garlic, fresh ginger, berries, green tea, and even grass fed butter and organ meat–full of vitamin A and other immune-boosting natural compounds.

Stay well, be healthy, and remember, a healthy body is the best defense against any disease.

We put one of the worst modern health crisis in our rear view mirror, but is it really over?

2026 – ER doc has urgent immunity warning for what’s coming

According to one ER doctor, there are 3 terrifying warning signs right now…

The media is hiding them (the politicians needed votes this fall).

Click here to see what’s coming next, and how to protect yourself

Immunity has been the perfect “back door” for taking away our freedoms..

And, what comes next could make the last few years look like a cakewalk.

Here’s this MD’s suggestions for supporting your immune system right now.

References
https://www.cbc.ca/radio/thecurrent/the-current-for-feb-28-2020-1.5479561/as-coronavirus-spread-speeds-up-montreal-researchers-will-trial-an-anti-viral-treatment-for-covid-19-in-china-1.5480134
https://regenexx.com/blog/coronavirus-episode-9-can-Quercetin-help-covid-19/
https://www.webmd.com/vitamins/ai/ingredientmono-294/Quercetin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808895/
https://jvi.asm.org/content/78/20/11334
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/quercetin
https://doi.org/10.26434/chemrxiv.11871402.v3

The post Quercetin vs Viruses (Powerful anti-viral properties of this unique nutrient) appeared first on thenutritionwatchdog.com.