This Artificial Sweetener is Promoted as “healthy”, but Can Damage Your Gut and Disrupt Your Microbiome

Don’t be fooled by clever marketing from the Big Food companies that promote this artificial sweetener as healthy… Some studies indicate this could be harming your gut health, which can indirectly cause weight gain, skin problems, autoimmune disorders, and more

by Catherine Ebeling & Mike Geary
co-author of the best-sellers:  The Fat Burning KitchenThe Top 101 Foods that Fight Aging & The Diabetes Fix

You are growing your own ‘critter’ collection in your gut all the time.does splenda damage your gut health?

In fact, right now, you are probably carrying around about several trillion of these critters. The hoards of bacteria that grow in your gut make up your own personal “microbiome”, and are of utmost importance to your health.  In fact, the microbiome and its effect on our overall health is still not fully understood by scientists, but we are learning more about it every single day as new research emerges all the time linking gut health to skin problems, autoimmune disorders, brain function, fat metabolism, and more.

Your unique microbiome is essential not only for good digestion, but also your ability to synthesize vitamins, maintain good immune function, prevent cancer and fight inflammation.

Gut bacteria also heavily influence whether you are overweight, obese or slender, and whether or not you get type 2 diabetes.

While it used to be thought that the bacteria that lived in our gut had little to do with other biological functions in our bodies, scientists have been studying specific strains of these bacteria and the significant roles they play in many diseases, including mental illness. Gut bacteria have been found to communicate directly with the huge numbers of nerve endings in the digestive system and nervous system overall, which then communicates with the body as a whole, including your brain.

In an article from Medical News Today, it was reported that, “According to the American Psychological Association (APA), gut bacteria produce an array of neurochemicals that the brain uses for the regulation of physiological and mental processes, including memory, learning and mood. In fact, 95% of the body’s supply of serotonin is produced by gut bacteria, according to the APA.”

Another researcher and specialist in bacterial health is Dr. Perlmutter, a board certified neurologist, and fellow of the American College of Nutrition. He has published his own studies in several prestigious peer-reviewed journals, as well as being the author of two best-selling books–Grain Brain and Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain – for Life.

According to Dr. Perlmutter, every system in your body is interrelated in a way that ultimately creates either health or disease. This becomes extremely important because when gut microbiome is off-balance, the lining of the gut can become compromised, creating a ‘leaky’ gut and inflammation—leading to a variety of health issues—including Alzheimer’s, Multiple Sclerosis, and Parkinson’s.

Says Dr. Perlmutter, “Our food choices have a dramatic effect on the health viability and even the diversity of those gut bacteria.

The healthy bacterial balance in our digestive systems can also change from good to bad from artificial sweeteners, most notably the newest zero-calorie sweetener, Splenda.  Splenda, also known as sucralose, is one of the newest artificial, chemical sweeteners.  Although Splenda has been advertised as being “made from sugar” implying that it is in some way “natural”, it in no way actually resembles sugar.  In fact, it is actually closer chemically to a chlorinated pesticide!

In 1998, Splenda was approved by the FDA as a general-purpose sweetener.

While the FDA claimed that over 100 animal and human studies were done, but only TWO of them were actually done on humans. Many people have reported adverse reactions to Splenda and it’s not surprising. Although Splenda starts off with a sugar molecule, it is processed with chlorine, which converts it into an unnatural sugar molecule, not recognized by our bodies.  And, a high percentage of sucralose is absorbed into the intestines.

Splenda (sucralose) has been shown, scientifically to kill off some of the important micro-organisms in your gut. The same healthy bacteria so vital to all healthy biological functions in the body. 

Is it any wonder why so many people who consume sucralose are reporting adverse health conditions?gut health

Recent studies from Canada show a correlation in huge increases in Inflammatory Bowel Disease incidence and the consumption of sucralose. Many IBD patients wind up having repeated surgeries to remove sections of their colon to address the ongoing inflammation which can result in result in devastating and life-threatening complications.

And, given the fact that Splenda kills off some of the most beneficial bacteria in the intestines, it’s no wonder people are being diagnosed with this debilitating disease. The Canadian Journal of Gastroenterology theorizes that the increase in IBD is related to an impairment of digestive enzymes, manufactured in our gut.  

In a 2008 study on Splenda from the Journal of Toxicology and Environmental Health, it was found that Splenda throws off the pH level in the intestines as well as killing off the beneficial bacteria, and adversely affecting a glycoprotein in the body that can have crucial health effects—particularly when taking certain medications such as cancer medication, treatments for AIDS or heart conditions.

James Turner, chairman of the national consumer education group Citizens for Health issued the following statement on this study:

“The report makes it clear that the artificial sweetener Splenda and its key component sucralose pose a threat to the people who consume the product. Hundreds of consumers have complained to us about side effects from using Splenda and this study … confirms that the chemicals in the little yellow package should carry a big red warning label.”

Given the above connections of gut bacteria and overall health issues, including brain health, you can certainly correctly assume that Splenda is going to be connected to quite a few serious health issues.

If you are experiencing any type of poor health—whether it is mental health issues, digestive issues, food allergies, or other more serious chronic health issues—it is definitely worth taking a look at your intake of artificial sweeteners, especially sucralose, and avoiding them!

Believe me, if you keep destroying up to half of your gut flora by regularly consuming Splenda, then poor health is virtually guaranteed!

Making matters worse, most people are already deficient in healthy bacteria due to excessive consumption of highly processed foods, which is why a high quality probiotic supplement is a good idea for most people, or a variety of fermented foods rich in probiotics. If you add sucralose to an already unbalanced intestinal tract, health problems will definitely ensue…

Some of the other commonly reported symptoms, usually experienced within 24 hours after consuming Splenda, according to the website, include:

  • Gastrointestinal problems, bloating, gas, diarrhea, vomiting
  • Blurred vision, red itchy eyes
  • Headaches, and Migraines
  • Allergic reactions, rashes, hives
  • Seizures, heart palpitations
  • Blood sugar increases, decreased sensitivity to insulin
  • Anxiety, depression, dizziness
  • Weight gain
  • Joint aches
  • Stuffy nose or sneezing

And long term use of Splenda in animals showed these serious health problems arise:

  • Decreased red blood cells, anemia
  • Male infertility
  • Brain lesions
  • Enlarged and calcified kidneys 
  • Spontaneous abortions
  • Higher death rate

While the typical Standard American Diet actually encourages the growth of certain harmful bacteria and yeast organisms, coupled with consumption of Splenda, which kills off the body’s beneficial bacteria, the path to disease and serious, and possibly deadly, health consequences seems likely.  Not to mention our overuse of antibiotics, which of course, can wipe out large portions of your gut bacteria, good and bad, leaving plenty of room for dangerous pathogens to take up residence, creating even more havoc to your physical and mental health.

A healthy diet low in processed flours, grains, sugars, and vegetable oils (essentially a “Paleo Diet”), can encourage the presence of good gut bacteria however, along with consuming plenty of REAL food such as fresh, raw, organic vegetables, berries, nuts, and other sources of healthy fats.

And one of the newer research findings in 2014, shows that exercise is also beneficial to gut bacteria diversity and culture.

So ditch the Splenda and ALL artificial sweeteners—they do way more harm than any good!

And follow these tips to regain that healthy balance and keep those critters in your gut happy.

1. Eat plenty of vegetables and small amounts of fruit

This is the key fuel for a healthy balanced microbiome, which feeds on certain types of vegetable fibers. Fruit is good too, but be careful, fruit can be high in sugar too, which can cause an overgrowth of unhealthy yeasts in the gut.  Most root vegetables are also great for gut health by feeding the good bacteria.

2. Enjoy your fermented foods

Kimchi, Tempeh, miso, sauerkraut (the kind that you buy cold, these have live probiotics), kombucha, raw apple cider vinegar, plain yogurt and kefir are all great. Even wine and dark chocolate are fermented and good for you in smaller doses.  Read Mike’s article The Truth about Yogurt for tips to make sure you’re getting yogurt that actually has live probiotics and health benefits, and to avoid the problems with many yogurt brands.

3. Avoid gluten, flours made from grains, and sugars

These foods encourage the growth of pathogenic bacteria and yeasts which can overtake the healthy flora in your gut.  

4.Take a broad spectrum probiotics supplement

It never hurts to supplement with a high quality probiotic that contains a wide variety of bacterial strains and large numbers of bacteria. This will help your overall health and choke out the unhealthy bacteria and yeasts that may be growing in your gut.

Also, collagen sources such as gelatin, bone broth and chicken feet broth are important foods to incorporate into your daily or weekly nutrition as the collagen helps heal leaky gut and is also very helpful for your joints too!

5. Use antibiotics VERY sparingly and only when absolutely necessary

This class of drugs is incorrectly prescribed way too often, when they are usually not needed.  If you keep your immune system strong through proper vitamin D3 levels, proper probiotic balance in your gut, enough restful sleep, and stress reduction, you can usually prevent yourself from getting sick in the first place.  Read Mike’s article with 7 tips to never get sick here.

And speaking of antibiotics, remember that commercially raised cattle, pork and dairy are fed antibiotics to encourage growth, and this is something you end up consuming, so chooose healthier pasture-raised meats which generally use much less antibiotics than grain-fed confinement meats.

6. Use a water filter on your tap water and shower head

Chlorine in water supplies is a major antibacterial compound, and you are exposed not only from drinking it, but you also soak it up through your skin from showering.

7. Get rid of antibacterial soaps and hand cleaners

Triclosan, which is the main ingredient in antibacterial soaps and cleaners, is one of the main causes of antibiotic resistance, and contributes to allergies, asthma and eczema. Using soap and water, and the friction from rubbing your hands together gets rid of germs, without antibiotic resistance.

The performance and well-being of your critters in your digestive system, your brain and your overall health are intricately tied together. Avoid artificial sweeteners as much as you can (choose natural STEVIA instead which is simply a natural herb), and remember when you eat, you are eating for several trillion of your friends in your gut!  Feed those critters what they need, and avoid the stuff that kills them, and your healthy body will thank you!

Mohamed B. Abou-Doniaa*, Eman M. El-Masrya, Ali A. Abdel-Rahmana, Roger E. McLendonb & Susan S. Schiffmanc, “Splenda Alters Gut Microflora and Increases Intestinal P-Glycoprotein and Cytochrome P-450 in Male Rats”, Journal of Toxicology and Environmental Health, Sept 2008.
Honor Whiteman, “The Gut Micobiome: how does it affect our health?”, Medical News Today, March, 2015.
Xiaofa Qin, MD, PhD, “What made Canada become a country with the highest incidence of inflammatory bowel disease: Could sucralose be the culprit?” Canadian Journal of Gastroenterology Sep 2011, (25)9:511-511.
Dr. Joseph Mercola, “Splenda, It Destroys Your Immune System and Is Like Eating Insecticide”, November 2011.
Dr. Joseph Mercola, “Splenda: The ‘Other’ Sweetener That’s Made from Sugar, but Is Closer to DDT”,, April 2011.

About The Watchdog

Mike Geary has been a Certified Nutrition Specialist and Certified Personal Trainer for over 15 years now. He has been studying nutrition and exercise for almost 25 years, ever since being a young teenager. Mike is originally from Pennsylvania, but has fallen in love with mountain life and now resides in the picturesque mountains of Utah. Mike is an avid adventurist and when he’s not spending his time skiing, mountain biking, hiking, or paddleboarding on the lake, he has enjoyed skydiving, whitewater rafting, piloting an Italian fighter plane (seriously), scuba diving, heli-skiing, and traveling all around the world, enjoying learning about different cultures. At the age of 40, Mike now feels healthier, stronger, and more energetic than when he was 20... All because of a healthy lifestyle and great nutrition!

Check Also


3 Scary Reasons To Ditch Aluminum Foil (And What To Use Instead)

Today’s blog is republished from my friends at TheAlternativeDaily, a leading publisher of daily alternative health …


  1. Hello Mike I wanted a copy of your fat burning programme so went for it a few moments ago , I have not taken you up on any of the other offers but the last page where I need to put my details it just says error and it does not go any further , I have clicked on the PayPal dispute page and clicked did not receive order , perhaps I should have seen you first as you are not probably aware of the error page regards Paul Jackson

  2. I was a week away from having an ablation of my heart due to wildly erratic PVC’s (premature ventricular contractions) when by sheer luck I discovered that what was at the root of my problem was sucralose (Splenda). I eliminated all forms of sucralose and the problem diminished to the extent that I was able to cancel the ablation procedure and return to a regular lifestyle. I had gotten to the point where 24.1% of my heartbeats were PVCs , or flutters. Now it’s about 1%. They shouldn’t be allowed to sell this garbage.

  3. Hello Mike Thank you for educative article about splenda indeed most of what we consume eg. loli pops juices bread softdrinks contain sucralose. Thank you very much for letting us know.

  4. That is very attention-grabbing, You’re a very professional blogger.
    I have joined your rss feed and look forward to in the hunt for extra of your excellent post.
    Additionally, I have shared your site in my social networks

  5. Pretty great post. I just stumbled upon your blog and wished to say that I’ve really loved surfing around your
    weblog posts. After all I’ll be subscribing to your
    feed and I hope you write once more soon!

  6. I just liкe the helpfᥙl infoormation youu supply tⲟ
    your ɑrticⅼes. I will bookmark your wsƄlog and check again here frequently.
    I aam somewhat sure I’ll be informed ⲣlenty off new stuff right right here!
    Best of luck for the following!

  7. accommodate all of your belongings.

    My brother suggested I would possibly like this blog.
    He used to be totally right. This submit truly made my day.
    You cann’t consider just how so much time I had spent
    for this information! Thanks!

  8. sinh trac dau van tay

    Great article.

  9. What’s up friends, its great paragraph regarding cultureand entirely defined, keep it up all the time.

  10. With all the chemicals and other “healthy JUNK” added to our foods and all the medical problems we have, you would THINK that being one of the BEST and SMARTEST countries in the world would regulate our foods much better than they do. I guess that says a lot about how things are run in our country. Some of the things that are added to our foods are BANNED in other countries! That’s how smart the FDA is. What a JOKE they are!
    However, if you’re up for a challenge, try eating fruits for two weeks, and wean yourself OFF of the things you add artificial sweeteners to. I lost my craving for sweets and sugar TOTALLY within 3 weeks of doing this!
    Besides that, it’s MUCH HEALTHIER!

  11. Great article.what can Splenda be replaced with?

    • Hi Anne, if you’re looking for a 0 calorie sugar substitute, Stevia is the way to go, and you only need to use a tiny bit. Other natural sugar alternatives are raw honey, coconut sugar, dates, …. Here are couple of articles with additional information on the topic

      • Big problem with Stevia is that the taste is horrible. I’ve tried it…. about 2 yrs later at a friends “insistance” I tried it again and threw it away… Doesn’t sweeten and the taste is awful. Maybe it’s one of those odd things that some can taste and others can’t.(like iodine in salt?).. but it’s god awful to me. I do use splenda, not heavily.. but If I drink any ice tea in the summer I lightly sweeten it with splenda as the taste is better. However I do not use it as directed… I use just under half of what is directed. Been 20 yrs, I’m perfectly healthy, no new illness, or conditions… I have diabetes, it is under control well now for yrs Had it long before splenda ever came out.. I’ve not gained weight… of course I could stand to loose a little, but not a great amount.. in fact I’m about 35 lbs less than I was 10 yrs or so ago.

        • In 1990, a friend of mine who was a very serious scientist at the C.N.R.S in France. Centre National de la Recherche Scientific and who worked with Dr. Luc Montagnier who isolated the AID virus… slouch. That friend told me that after all their research Aspartame, Splenda.was safe . That all that fuss here made in the USA ( where he worked in research for many years also) was a conspiracy to keep American fat and the diabetic pharma. rolling.

    • I don’t use sugar. I use instead raw unfiltered honey and organic pure maple syrup.

  12. Did you know that the FLAVORED forms of Pedialyte that are given to our infants for rehydration contain this harmful chemical called sucralose? Abbott created the flavored forms to get higher retail distribution of their product. Our infants don’t need flavored Pedialyte. It’s all about marketing and not good medicine. The chronic consumption also causes irregular heart beat that leads to ablation. Where are our concerned medical leaders at the FDA to stop the harm that is being caused by Splenda. J&J created Splenda and sold the business for $300 million. Do you think they may have recognized the potential for harm and didn’t want the liability? They have 1000’s of lawsuits pending for other products that they have marketed with out proper testing to make sure they do no harm.

  13. Fantastic web site. A lot of helpful info here.
    I’m sending it to a few buddies ans also sharing in delicious.
    And naturally, thank you to your sweat!

  14. Thanks for the article. I have figured out by trial and err that all artificial sweeteners cause me severe migraine, which return for three to 4 consecutives days. Stevia is good, however be aware that most commercial ones are loaded with Maltodextrin, which also causes me severe headache.

  15. I have been using stevia as a sweetener for 10 years and it has not harmed me in any way and it is all
    natural, [ no chemicals ] and it makes a great sweetener in any kind of drink. I even use it to disguise the
    awful taste of apple cider vinegar.

    Dan O’Connor

  16. Right here is the right web site for anybody who really wants to
    understand this topic. You realize so much its almost hard
    to argue with you (not that I actually will need to…HaHa).
    You definitely put a new spin on a topic that’s been written about for years.
    Great stuff, just excellent!

  17. Just a couple of observations. I’ve never used Splenda or sucralose. If I use a substitute at all it is Stevia. But I tend to use honey and raw unwashed sugar. For salt, we only use sea salt or the Himalayan salt. No refined salt or sugar is used at our house.

    The only other observation I’ll make is that the use of gluten free products is NOT a healthy choice unless you have celiac or another allergy. I have seen several studies that have shown gluten free in an otherwise person is not a good thing. I’m, frankly, too lazy to go hunt the studies up now.

  18. Our grocery store shelves are loaded full of products that contain substances known to be toxic and not healthy for human consumption, with more being added all the time, all in the name of the Almighty Dollar. Then to add insult to injury, they try to coerce you and manipulate you into buying this poisonous processed food with slick images on the containers, and carefully scripted, highly manipulative TV commercials and ads in magazines.

    If you’re a conscientious label reader, then you know just how pervasive sucralose is, being added to nearly every sweetened item from bottled coffee, energy drinks, to cake mixes, and even protein supplements for bodybuilders.

    It’s hard to find any product that doesn’t contain it these days, hell, it’s even in Jello and jello pudding. It’s just everywhere. and no, the FDA does not care about keeping our food sources safe and healthy i this country at all. They’re only interested in the billions of dollars they receive through their application and licensing processes, and have proven they can be easily bribed with a few million dollars any day of the week and will accept bogus studies without question.

    It’s a constant battle to stay informed, to constantly read labels, and to attempt to eat good, nutritious, healthy, life producing food, with over 90% of what’s sold in the stores not being fit for human consumption and containing items that cause health problems and diseases over the long term.

    The obesity and health crisis in this country has long been determined to be caused by one thing – the unhealthy substances we have to choose from in the grocery stores, from which most people make their chaises based solely by how good something tastes, even if it’s artificially flavored and colored, full of preservatives, has artificial sweeteners, and is of low or no nutritional value at all.

    Sucralose is everywhere, and it’s like a nuclear bomb going off in your gut, decimating the good gut bacteria you need for optimum health, even if you don’t feel it’s doing you any harm and you think ( at least for now), you’re in good health. It’s sweet tasting poison, pure and simple. Long term studies have proven it causes tumors, as well, which the FDA chooses to ignore.

  19. WOW!!! No wonder the American people are so sick so often. It’s a known fact that the pharmaceutical industry pays the FDA. It’s also known that big pharma has cures for unpopular ailments that won’t produce many, many millions of dollars. What a shame!!! We are led by extreme greed at the expense of human life. How can we end these injustices?

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.