Ashwagandha – 9 powerful health benefits of this super-herb (including Thyroid health, Adrenal health, blood sugar, anxiety, and more)

by Catherine Ebeling 
co-author of the best-sellers:  The Fat Burning KitchenThe Top 101 Foods that Fight Aging & The Diabetes Fix

The supplement section of my health food store carries these cute little bottles, with curious labels, like “I am Happy”, “I am Sleepy”, “I am Focused”, “I am Energized”, etc. Sort of reminds me of Alice in Wonderland. Curious, one day I tried the “I am Happy” bottle, because who doesn’t like being happier? (Although I am generally a very happy person, which I attribute to healthy diet, healthy gut bacteria, and plenty of exercise!)

Drinking the “I am Happy” potion made me feel noticeably calmer, happier, and focused. When I checked out the ingredients on the label, I found the primary ingredient was Ashwagandha. No wonder! Now I take ashwagandha supplements daily. Here’s why…

Research on Ashwagandha, or withania somnifera, shows it is an amazing herbal supplement that has been used for hundreds of years, with impressive benefits including:  thyroid health, lowering or maintaining blood sugar levels, helping to reduce body fat, reducing stress and (fat-storing) cortisol, increasing mental focus and brain function, increasing endurance, and counteracting anxiety and depression. I AM happy to discover that!

Ashwagandha is considered an Ayurvedic medicine and is a powerful adaptogenic herb. Adaptogens have very unique properties that help your body adapt to stress. In order to be classified as an adaptogen, they must have balancing properties and work on multiple biological and physiological levels. For example, ashwaganda works to balance blood sugar by lowering it in people with elevated blood sugar and helping to raise it in those who may be hypoglycemic. It has the ability to help hypothyroid sufferers as well as hyperthyroid folks. No pharmaceuticals that I know of, can claim these unique balancing benefits.

While ashwaganda is best known for its ability to reduce stress and cortisol—a harmful hormone by-product of stress, it also has far reaching benefits for the whole body.

Reduces Chronic Stress, Cortisol and Adrenal Fatigue

Chronic stress can become very problematic to our health over time. During periods of high stress, the adrenal glands produce too much cortisol. This can result in chronically high blood sugar levels, which makes one more susceptible to diabetes, and chronic hunger—leading to weight gain. Excess cortisol also inhibits the body’s immune response, making it more easy to catch common illnesses like colds and flu, but also more serious stuff like pneumonia, and even cancer. Cortisol also inhibits digestion, exacerbating digestive issues, like heartburn and constipation or diarrhea. Cortisol also causes problems with blood pressure, cholesterol levels, and sleep.

When adrenal glands become overused, adrenal fatigue results. Unfortunately, adrenal fatigue starts a chain reaction that can also affect progesterone (in women), which is also a calming hormone, as well as affecting fertility and pregnancy—and DHEA (in men and women) which is a precursor to sex hormones, fights aging and adds stamina. Ashwagandha has been scientifically studied and has been found to not only reduce cortisol and C-reactive protein (CRP), but also to reduce stress, increase DHEA, lower blood pressure and heart rate, support the adrenal glands and even improve fertility issues.

Prevents and Helps Treat Cancer

Ashwagandha is also a powerful weapon against cancer. Not only does it show possible benefits in fighting existing cancer cells, but it also impedes the growth of new cancer cells. Animal studies show ashwagandha to be effectively beneficial against breast, lung, colon, brain and even ovarian cancer. In a study on mice with ovarian cancer, the mice who were given ashwagandha or a combination of ashwagandha and an anti-cancer medication, and had a 70-80% reduction in tumor growth and metastasis—that’s pretty significant!

It is thought that ashwagandha’s power against cancer may stem from it’s ability to boost the immune system, and its antioxidant power. Ashwaganda is known to increase white blood cell function, which is the body’s primary army against disease pathogens, including cancer. Ashwaganda also has a unique ability to stop the growth of blood vessels around cancer cells and tumors, thereby helping to starve cancer cells of necessary nutrients needed to survive.

Ashwagandha is also a partner to traditional chemotherapy for cancer. While most chemo treatments suppress immune function, ashwagandha, in combination with chemotherapy, actually allows the immune system to function better. This keeps cancer patients from being at such a high risk for developing infections and catching communicable diseases. Cancer experts are actually now beginning to recommend ashwagandha for both cancer prevention and cancer treatments.

Thyroid health

As an adaptogen, ashwagandha helps to balance hormones, including thyroid hormone. In one study on mice, it was found that ashwaganda increased both T3 and T4 hormones after 20 days. Ashwaganda’s properties help to increase the overall function of the thyroid gland, including two of its principle thyroid hormones.

Ashwagandha can also help to balance out hyperthyroid issues as well, with its unique adaptogenic compounds. One important note for those on thyroid medication—since ashwagandha can affect thyroid hormone levels, be cautious when taking it, or ask your doctor.

How to lose weight when your thyroid is messed up

Boosts Brain Function, Decreases Anxiety and Depression

Ashwagandha contains the ability to bring about calmness, focus and raise mood, partly because it not only decreases cortisol, but it also helps to regulate key brain neurotransmitters, including serotonin—that ‘happy’ brain chemical and GABA, a beneficial calming and inhibitory neurotransmitter that is involved with anxiety disorders, insomnia, and muscle spasms.

In fact, in a recent study on ashwaganda on anxiety and depression, the results were comparable to the pharmaceutical drugs lorazepam and imipramine without harmful side effects that these drugs produce. In one study 300mg of ashwagandha, twice a day helped to reduce anxiety, improve focus, reduce stress, and decrease fatigue.


Ashwagandha’s powerful anti-inflammatory properties also protect the brain from degeneration, protect the neurons, and improve symptoms of Alzheimer’s. It is thought that the naturally occurring antioxidants in ashwagandha may help eliminate the free radicals that attack the brain and cause inflammation that is one of the hallmarks of Alzheimer’s disease.

Results from one study on mice by the National Brain Research Centre showed after supplementing with ashwagandha for 20 days, the mice showed markedly improved retention and memory, with a reduction in the amyloid plaques, which are a hallmark of Alzheimer’s disease.

Blood Sugar Control, Triglycerides and LDL Cholesterol

Several studies on ashwagandha and the blood show it highly effective in balancing or lowering blood sugar, as well as increasing insulin secretion and improving insulin sensitivity. Not only does it help to regulate blood sugar in those with diabetes, but it also helps to lower blood sugar levels in healthy people—which is a good thing. Studies have shown that higher blood sugar levels in even healthy individuals can raise the risk for heart disease, strokes, and even cancer.

Several human studies have confirmed its ability to reduce blood sugar levels in people with and without diabetes, and those whose blood sugar levels were elevated as a side effect of medication. In one study on patients with schizophrenia with elevated blood sugar from antipsychotics, those on ashwaganda had an average reduction in fasting blood sugar of 13.5mg/dL. And in one other small study of type 2 diabetics, it was reported that supplementing with ashwagandha for 30 days lowered their fasting blood sugar levels as effectively as a popular oral glycemic medication.


Because ashwagandha helps to regulate blood sugar, it also helps to lower triglycerides (which can be a result of high blood sugar.  Not only does it help to lower triglycerides, but it also helps to lower the more harmful type of cholesterol, LDL.  One study in rats found it lowered total cholesterol as much as 53% and triglycerides by 45%. And another study on human subjects LDL cholesterol decreased by 17%.

Boosts Testosterone and Increases Fertility

Ashwaganda’s positive effects on hormones in the body continue with testosterone. In one study of 75 infertile men, the group treated with ashwaganda had a noticeable increase in sperm count and motility. And this treatment jacked up their testosterone as well! And another study on ashwaganda and stress, showed that the men not only experienced a reduction in stress and an increase in antioxidants—but on top of that, 14% of the men’s partners became pregnant due to the increase in sperm count and motility.  (Note for men interested in learning more about Testosterone, read this article:  7 foods that boost your sagging Testosterone)

Athletic Performance

Ashwagandha should be in every athlete’s supplement cabinet. Studies show it can actually boost endurance. It is thought this is because it not only sharpens brain activity, but reduces pain and inflammation, and lowers stress hormones. One scientific study on rats showed that they were able to swim twice as long as the test group.

Ashwagandha’s ability to balance adrenal hormones that build up over prolonged physical activity, combined with its ability to reduce inflammation, as in sore muscles and joints, and keep energy levels steady, can give competitive (or non-competitive) athletes an edge over their competition. Some studies also show ashwagandha’s ability to help with actual muscle gain and fat loss, as well as increasing strength.

Decreases Harmful Inflammation

Inflammation is one of the hallmarks of disease, and chronic inflammation can cause everything from heart attacks and diabetes, to arthritis and joint pain. Reducing inflammation is a key to maintaining good health. Ashwagandha helps improve joint pain in those who have arthritis, as well as increasing the body’s natural killer cells, which are the immune system’s first line of defense against harmful pathogens. Many pharmaceutical anti-inflammatories contain steroids which actually reduce immune system function.


Ashwagandha’s anti-inflammatory action also extends to reducing levels of C-reactive protein, a harmful inflammatory compound that is one of the key markers and risk factors for heart disease. This controlled study found a 36% decrease in CRP in the group taking 250mg of ashwagandha daily.

How to Take Ashwagandha

Ashwaganda is a safe supplement for most people but if you are pregnant or breastfeeding, avoid it until you check with your doctor. People with autoimmune diseases such as rheumatoid arthritis, lupus, Hashimoto’s thyroiditis, and type 1 diabetes should also avoid taking it unless cleared by a physician.

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Axe, Josh, DNM, DC, CNS. (2016). Ashwaganda benefits thyroid and adrenals. Retrieved from
Biswajit, A., Jayaram, H., Achintya, M., Bruce, A., Shibnath, G., (2014). Parameters in standardized withania somnifera extract significantly reduces stress related parameters in chronically stressed humans, a double blind randomized, placebo controlled study. Retrieved from
Bhattacharya, S. K. and Muruganandam, A. V. (2003). Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress. Pharmacol Biochem.Behav 2003;75(3):547-555.
Chang, Pohling, Natarajan, Witney, Kaur, Xu, Gowrishankar, D’Souza, Murty, Schick, Chen, Wu, Khaw, Mischel, Abbasi, Usmani, Mallick, Gambhir. (2016). AshwaMAX and Withaferin A inhibits gliomas in cellular and murine orthotopic models.
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Kakar, Ratajczak, Powell, Moghandamfalahi, Miller, Batra, Singh. (2012). Withaferin a alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells. PLoS One. 2014 Sep 29;9(9):e107596. doi: 10.1371/journal.pone.0107596. eCollection 2014. Retrieved from
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About The Watchdog

Mike Geary has been a Certified Nutrition Specialist and Certified Personal Trainer for over 15 years now. He has been studying nutrition and exercise for almost 25 years, ever since being a young teenager. Mike is originally from Pennsylvania, but has fallen in love with mountain life and now resides in the picturesque mountains of Utah. Mike is an avid adventurist and when he’s not spending his time skiing, mountain biking, hiking, or paddleboarding on the lake, he has enjoyed skydiving, whitewater rafting, piloting an Italian fighter plane (seriously), scuba diving, heli-skiing, and traveling all around the world, enjoying learning about different cultures. At the age of 40, Mike now feels healthier, stronger, and more energetic than when he was 20... All because of a healthy lifestyle and great nutrition!

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  1. great article.been taking this for about 6 months and i have noticed a difference in my mood..however i have 2 questions..can this be taken every day with no break?..and i have heard that ashwagandha can give a false positive on a drug test,is this true…thanks

    • I don’t know, but i have taken Ashwanghanda every day for three months now and i feel fine. I feel much better. I was more depressed. It helps me a lot. I only take it once a day or twice if i am more stressed.

    • This is a good question .? So do u fail a drug test

  2. I really like RealDose Weight Loss Formula No1 .But I can’t find were to order it in Australia ? Could you let me now email or phone to place an order

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    And i’m glad reading your article. But want to remark on few general things, The
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    nice : D. Good job, cheers

  4. lots of good info on this site

  5. wonderful sight to get health related informations

  6. Hi,
    I started taking ashwagandha for low adrenal and it made me very tired. Was only taking it once a day. What does this mean and what do you suggest? Thank you for any info you can provide.

  7. There is no where to UNSUBSCRIBE! So please do so. THANK YOU!

    • Hi Donna, to Unsubscribe from receiving emails please select ‘Manage Subscription’ (located at the bottom of the emails you receive from us) then select ‘Never email me again’.

    • Why should people with autoimmune issues, lupus, etc…not take this?

  8. The green drink you’re talking about is it called Organtify

  9. How does Ashwaganda affect low blood sugar

  10. Hi, my naturopathic doctor said not to take adaptogens like ashwaganda for more than three months at a time. She said take a break and then go back to it.
    I love ashwaganda and had more energy and lost weight. I will start it again.

  11. Interested in getting ashwaganda

  12. Can you explain why you stated in your article that people with Hashimotos should not take ashwaganda. Thank you.

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